POD 102: A self-taught chemist's journey to synthesize 5-MeO-DMT
🕑 Added 2024-04-28 07:46:24 +0000 UTCIn this interview I talk with a completely self-taught chemist about his experience reading the Bufo alvarius pamphlet and deciding to embark on a tryptamine chemistry quest. The discussion covers DMT, 5-MeO-DMT, NsBT, 5-MeO-NsBT, 5-MeO-MsBT, and the use of 5-MeO-MiPT to treat ankylosing spondylitis.
NOTE: Any Patreon who signed up to a higher tier to ask a question for this month’s Q&A will receive according priority next month.
NOTE 2: Synthesis notes are incoming

Comments
Siddhesvhvara
As Hamilton mentions, this man maybe unintentionally understates the emotional tolls suffered when operating in this capacity in an attempt to avoid sounding like he's complaining. However his voice and word choices explaining the abject isolation and loneliness involved in the work resonated deeply with me and I had to stop the recording for a moment. Obviously I am not sure who any of you here are or what any of you do in your lives but I hope you all learn everything you hope to in your endeavors all the while staying vigilantly secure in your operations... The loneliness and isolation the gueat mentions are so very real. Stay healthy and balanced in all you do, friends. Take extra measures to ensure your emotional and mental well-being no matter who you are, but especially so if you are one of those who channel Kid Charlemagne
Singleton
Hey all. Sorry to necro, but did anyone get a handle on this synth?
Jack Alderton
Iv definitely seen 1kg scale b-3,4,5-TMONS reduction using CuCl2 and NaBH4
Jack Alderton
Yeah I’d say CuCl2 and NaBH4 for reduction of mescaline and most phenethylamines ime
Oli
Any word on those incoming synthesis notes? :)
Jamie Howell
His description of 30mg of 5meo sounds exactly like one of the B.P.M.'s from "the way of the psychonaut" . The memory of being birthed in the hospital.
Jack Alderton
One thing….he is using borohydride also, and he is having re-x problems from hexane. Would you suggest ethyl acetate instead? Seems to be very ‘oily’
Jack Alderton
I actually thought tryptamine was fairly cheap tbf. Also re the lab, you don’t NEEED it. You need a stirrer that’s about it…it’s nice to have all this. My friend just did a DMT synth with an ice bath and actually got a higher yield than when he ran it at a lower temp….love it
Klyne Lynch
Wow what a wonderful interview. Thank you
Hamilton Morris
No, it is not feasible.
twinghost333
Is it feasible to extract dmt from psilocin
Honey-el
I understand nothing of chemistry but I enjoyed the guy's clarity of verbalization, especially when he was describing his internal experiences.
Andy Braham
Why no rectal? Your show had many anus references. You seem have a keen interest in “anality” in general. That lemon shirt. The fistula reference.