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Q&A Podcast this September! How to Submit your questions

🕑 Added 2023-08-31 01:52:14 +0000 UTC

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Tamper Tantrum

A reliable yet rudimentary way to test shared hallucinations is with before and after testing with mosquito ringtones. https://www.audiocheck.net/audiotests_mosquito.php This can most likely be done even with low dose LSD and Psilocybin mushrooms.

Hamilton Morris

Which prodrug, serdexmethylphenidate?

Igor Żmójdzin

Yeah, Lizard Labs guy is very interesting.

B-Boy Bungus

Any chance of you reaching out to Strike (Hobart Huson) for an interview? What about Maia Szalavitz? Also, when will we get the Stanton Peele interview? Wasn't there also a mention of a Lizard Labs episode? Appreciate you Hamilton! Thanks!

david

MBH, just back from a neuropharm meeting . . . the psych industry is courting the non-trad meds for MDD hard, mostly glutamate and gabanergic to ultimately hit AMPAR, NMDAR and BDNF translation for rapid healing. Good results overall and suggesting that SSRI will mostly be just a part of history. Dextromethorphan is being repurposed by 3 companies, paired with 3 different CYP2D6 inhibiting drugs (quinidine, bupropion, forgot the 3rd) to triple the DXM half life. DXM has NMDA antagonism. Crazy expensive drug. You could just buy some cough syrup and Welbutrin. Vyvanse team has a new ADHD prodrug tied to dextro-methylphenidate that is dexMPH to N-carboxylate ester to quaternized niacin-amide to serine. H, you might want to interview the chemist who described how they make this crazy pro-drug that is GI metabolized. Smart PhD chemist who pioneered some important aspects of HIV drugs in the early 90s. Got his contact.

I saw a news report of a new synthetic opioid named - Isotonitazene (aka nitazene or "ISO")- being used to make other drugs more potent kinda like we saw when fentanyl came into the picture. Only difference is Nitazene was never FDA cleared in the U.S and is being sourced from China.

Toby Powell

I love you Hamilton! Have a good time bro you mean so much to me.


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