GordoTEK
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Harmala research
🕑 Added 2018-07-19 22:16:14 +0000 UTCI mentioned in my last video that sublingual absorption of harmalas is the most efficient way to get it into the human body, but since no studies have been published on this (as far as I know) I wasn't sure what an effective dose might be for the purposes of vaped DMT (plenty of studies have been published on oral harmalas and DMT). Through experimentation I have found that cutting the dose to just 75mg of a half THH half harmine/harmaline mix I recommend in my last video, taken sublingually for 10 minutes, worked perfectly for vaped DMT, I noticed no difference in duration or intensity/sensitivity to the DMT compared to a much higher dose of the harmala mix. Note that for just harmine alone most people will only need to use between 40-50mg, and for harmaline alone only 30-50mg are required. I am quite pleased that these compounds can be stretched this far. Also after doing more searching, I found the following study which may shed at least a little more light, these guys compared sublingual vs oral absorption of norharman in humans, this is a different beta carboline but probably shares some similarities with regard to absorption rate and bioavailability to the beta carbolines we are interested in: https://www.ncbi.nlm.nih.gov/pubmed/11669455
They found that the sublingual route resulted in a remarkable 65-fold increase in bioavailability compared to oral ingestion! Another nice benefit from the lower dosage is a complete lack of any nausea whatsoever.
Comments
monom
Thanks for your amazing work Gordo! Maybe you know the answer to the following question: Given that harmala freebase is insoluble in water how come it is active subliminally ? or did you use the salt form of it ?
portalman
Hi Gordo Tek - Thanks for all your interesting, good work! A question: I am looking to use the harmala mix you recommend for DMT and doing it with psilocibin (powdered MM). With the DMT I did exactly as you said, which as I remember was about 120 mill of harmala with 55 DMT (harmala taken pre and with, 10 minute interval). There was a little 'wretching' and spittle but nothing major. Normally I like a dose of 4 grams of MM. What adjustments would you recommend for "psilohuasca?" BTW your videos made all of this possible ('cept the MM). Even made your vape tool. Works but I'm reluctant to assault my lungs. Wondering whether I can get the same effect through pharmauasca as with vaping. Cheers! (not a patron of Gordo TEK but did make one-time donation)
